ARTHROSIS

ARTICANI clinical study

Inclusion-phase completed

Verification of the safety of intra-articular canine neonatal stem-cell administration.

• Monitoring spanning 6 months after administration has not shown associated side-effects
• Moderated local increase in temperature in the 48 hours following injection (consequence of the medical act)
• Confirms an excellent safety-profile

Comparison of clinical score and locomotion in dogs that were treated by surgery (tibial-plateau-leveling osteotomy or TPLO) and nonsteroidal inflammatory drugs (NSAIDs) or administered stem-cells

• No lameness has been associated with stem-cell treatment
• Similar clinical scores as established by veterinarians between the two groups
• Similar clinical scores as established by owners
• Stem-cells can be administered to NSAID-intolerant dogs previously treated by TPLO

Arthrosis-progression is evaluated in both groups.