J – Biosafety evaluation of equine umbilical cord-derived mesenchymal stromal cells (UC-MSCs) by systematic pathogen screening in peripheral maternal blood and paired UC-MSCs

– Denys, A – Léon, A – Robert, C – Saulnier, N – Josson-Schramme, A – Legrand, L -Wimel, L – Maddens, S ? Pronost,

I – Differences in the intrinsic chondrogenic potential of equine umbilical cord matrix and cord blood mesenchymal stromal/stem cells for cartilage regeneration

– Rodolphe Rakic, Bastien Bourdon, Magali Demoor, Stéphane Maddens, Nathalie Saulnier, Philippe Galéra Scientific Reports. 2018.

H – RNA Interference and BMP-2 Stimulation Allows Equine Chondrocytes Redifferentiation in 3D-Hypoxia Cell Culture Model: Application for Matrix-Induced Autologous Chondrocyte Implantation

– Rodolphe Rakic, Bastien Bourdon, Magalie Hervieu, Thomas Branly, Florence Legendre, Nathalie Saulnier, Fabrice Audigié, Stéphane Maddens, Magali Demoor, Philippe Galera – Int. J. Mol. Sci. 2017

G – Intra- articular administration of xenogeneic neonatal Mesenchymal Stromal Cells early after meniscal injury down-regulates metal- loproteinase gene expression in synovium and prevents cartilage degradation in a rabbit model of osteoarthritis.

Saulnier N, Viguier E, Perrier-Groult E, Chenu C, Pillet E, Roger T, et al. Osteoarthr Cartil. 2015.

E – Comparison of efficacy and safety of single versus repeated intra-articular injection of allogeneic neonatal mesenchymal stem cells for treatment of osteoarthritis of the metacarpophalangeal/metatarsophalangeal joint in horses: A clinical pilot study.

Carmelo Magri, Michael Schramme, Marine Febre, Eddy Cauvin, Fabrice Labadie, Nathalie Saulnier, Isé François, Antoine Lechartier, David Aebischer, Anne-Sophie Moncelet, Stéphane Maddens. Plos One. 29 Août 2019.

For Veterinarians only

For Veterinarians only

Ask your veterinarian for the price of a stem cell injection at his clinic.

Product Pipeline

Range Product Development & optimization Proof of Concept Pilot study Industrialisation /
Manufacturing
Pivotal study Approval Marketing Launch

CANIPREN

VBX-01
Canine osteoarthritis

CA0102
Atopic dermatitis

CA0103
Atopic dermatitis
Chronic
Inflammatory
Bowel
Disease

Range Product Development & optimization Proof of Concept Pilot study Industrialisation /
Manufacturing
Pivotal study Approval Marketing Launch

FELIPREN

FE0101
Gingivostomatitis

FE0102
Chronic kidney
failure

FE0103
Feline arthrosis

Range Product Development & optimization Proof of Concept Pilot study Industrialisation /
Manufacturing
Pivotal study Approval Marketing Launch

EQUIPREN
OMBISTEM

EQ0101
Equine arthrosis